165Er: A new candidate for Auger electron therapy and its possible cyclotron production from natural holmium targets
dc.contributor.author
Gracheva, Nadezda
dc.contributor.author
Carzaniga, Tommaso S.
dc.contributor.author
Schibli, Roger
dc.contributor.author
Braccini, Saverio
dc.contributor.author
van der Meulen, Nicholas P.
dc.date.accessioned
2020-02-21T08:54:35Z
dc.date.available
2020-02-21T03:23:23Z
dc.date.available
2020-02-21T08:54:35Z
dc.date.issued
2020-05
dc.identifier.issn
0969-8043
dc.identifier.issn
1872-9800
dc.identifier.other
10.1016/j.apradiso.2020.109079
en_US
dc.identifier.uri
http://hdl.handle.net/20.500.11850/400885
dc.identifier.doi
10.3929/ethz-b-000400885
dc.description.abstract
165Er, a pure Auger-electron emitter, could be an attractive candidate for targeted radionuclide therapy. Auger electrons possess short penetration paths with high linear energy transfer. In this study, experimental cross-sections of the 165Ho(p, n)165Er nuclear reaction were measured and targets irradiated with protons using Injector II cyclotron at Paul Scherrer Institute (Switzerland) and the 18 MeV medical cyclotron laboratory at the University Hospital in Bern. A purification method was developed in order to obtain 165Er suitable for in vivo applications.
en_US
dc.format
application/pdf
en_US
dc.language.iso
en
en_US
dc.publisher
Elsevier
en_US
dc.rights.uri
http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subject
165Er
en_US
dc.subject
Auger electrons
en_US
dc.subject
Cyclotron
en_US
dc.subject
Cross-section
en_US
dc.subject
Chemical separation
en_US
dc.title
165Er: A new candidate for Auger electron therapy and its possible cyclotron production from natural holmium targets
en_US
dc.type
Journal Article
dc.rights.license
Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
dc.date.published
2020-02-12
ethz.journal.title
Applied Radiation and Isotopes
ethz.journal.volume
159
en_US
ethz.journal.abbreviated
Appl. radiat. isotopes
ethz.pages.start
109079
en_US
ethz.size
8 p.
en_US
ethz.version.deposit
publishedVersion
en_US
ethz.identifier.wos
ethz.identifier.scopus
ethz.publication.place
Amsterdam
en_US
ethz.publication.status
published
en_US
ethz.leitzahl
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02020 - Dep. Chemie und Angewandte Biowiss. / Dep. of Chemistry and Applied Biosc.::02534 - Institut für Pharmazeutische Wiss. / Institute of Pharmaceutical Sciences::03688 - Schibli, Roger / Schibli, Roger
ethz.leitzahl.certified
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02020 - Dep. Chemie und Angewandte Biowiss. / Dep. of Chemistry and Applied Biosc.::02534 - Institut für Pharmazeutische Wiss. / Institute of Pharmaceutical Sciences::03688 - Schibli, Roger / Schibli, Roger
ethz.date.deposited
2020-02-21T03:23:32Z
ethz.source
SCOPUS
ethz.eth
yes
en_US
ethz.availability
Open access
en_US
ethz.rosetta.installDate
2020-02-21T08:54:46Z
ethz.rosetta.lastUpdated
2024-02-02T10:28:03Z
ethz.rosetta.versionExported
true
ethz.COinS
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