165Er: A new candidate for Auger electron therapy and its possible cyclotron production from natural holmium targets
Abstract
165Er, a pure Auger-electron emitter, could be an attractive candidate for targeted radionuclide therapy. Auger electrons possess short penetration paths with high linear energy transfer. In this study, experimental cross-sections of the 165Ho(p, n)165Er nuclear reaction were measured and targets irradiated with protons using Injector II cyclotron at Paul Scherrer Institute (Switzerland) and the 18 MeV medical cyclotron laboratory at the University Hospital in Bern. A purification method was developed in order to obtain 165Er suitable for in vivo applications. Show more
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https://doi.org/10.3929/ethz-b-000400885Publication status
publishedExternal links
Journal / series
Applied Radiation and IsotopesVolume
Pages / Article No.
Publisher
ElsevierSubject
165Er; Auger electrons; Cyclotron; Cross-section; Chemical separationOrganisational unit
03688 - Schibli, Roger / Schibli, Roger
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