Activation of Primary and Secondary Benzylic and Tertiary Alkyl (sp(3))C-F Bonds Inside a Self-Assembled Molecular Container
dc.contributor.author
Köster, Jesper M.
dc.contributor.author
Häussinger, Daniel
dc.contributor.author
Tiefenbacher, Konrad
dc.date.accessioned
2019-02-25T09:14:04Z
dc.date.available
2019-01-16T03:36:22Z
dc.date.available
2019-02-25T09:14:04Z
dc.date.issued
2019-01
dc.identifier.issn
2296-2646
dc.identifier.other
10.3389/fchem.2018.00639
en_US
dc.identifier.uri
http://hdl.handle.net/20.500.11850/316153
dc.identifier.doi
10.3929/ethz-b-000316153
dc.description.abstract
Alkyl fluorides are generally regarded as chemically inert. However, several literature examples describe the activation of alkyl (sp3)C-F bonds via strong Brønsted or Lewis acids under harsh conditions. We here report that catalytic amounts of the self-assembled resorcinarene capsule are able to activate alkyl (sp3)C-F bonds under mild conditions (40°C, no strong Brønsted or Lewis acid present). Kinetic measurements display a sigmoidal reaction progress after an initial induction period. Control experiments indicate that the presence of the supramolecular capsule is required for an efficient reaction acceleration.
en_US
dc.format
application/pdf
en_US
dc.language.iso
en
en_US
dc.publisher
Frontiers Media
dc.rights.uri
http://creativecommons.org/licenses/by/4.0/
dc.subject
supramolecular catalysis
en_US
dc.subject
molecular capsules
en_US
dc.subject
supramolecular chemistry
en_US
dc.subject
acid catalysis
en_US
dc.subject
elimination
en_US
dc.title
Activation of Primary and Secondary Benzylic and Tertiary Alkyl (sp(3))C-F Bonds Inside a Self-Assembled Molecular Container
en_US
dc.type
Journal Article
dc.rights.license
Creative Commons Attribution 4.0 International
dc.date.published
2019-01-04
ethz.journal.title
Frontiers in Chemistry
ethz.journal.volume
6
en_US
ethz.pages.start
639
en_US
ethz.size
7 p.
en_US
ethz.version.deposit
publishedVersion
en_US
ethz.identifier.wos
ethz.identifier.scopus
ethz.publication.place
Lausanne
ethz.publication.status
published
en_US
ethz.leitzahl
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02060 - Dep. Biosysteme / Dep. of Biosystems Science and Eng.::09585 - Tiefenbacher, Konrad / Tiefenbacher, Konrad
en_US
ethz.leitzahl.certified
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02060 - Dep. Biosysteme / Dep. of Biosystems Science and Eng.::09585 - Tiefenbacher, Konrad / Tiefenbacher, Konrad
ethz.date.deposited
2019-01-16T03:36:24Z
ethz.source
WOS
ethz.eth
yes
en_US
ethz.availability
Open access
en_US
ethz.rosetta.installDate
2019-02-25T09:14:15Z
ethz.rosetta.lastUpdated
2024-02-02T07:13:33Z
ethz.rosetta.versionExported
true
ethz.COinS
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