Combination of a microfluidic device and fluorescence correlation spectroscopy to study peptide translocation across model membranes
dc.contributor.author
Bachler, Simon
dc.contributor.author
Lin, Chao-Chen
dc.contributor.author
Dittrich, Petra S.
dc.date.accessioned
2021-03-17T09:40:46Z
dc.date.available
2018-01-15T14:38:37Z
dc.date.available
2018-03-09T16:40:15Z
dc.date.available
2019-09-11T12:20:17Z
dc.date.available
2020-02-17T10:12:13Z
dc.date.available
2020-02-20T09:02:07Z
dc.date.available
2021-03-17T09:40:46Z
dc.date.issued
2017
dc.identifier.isbn
978-0-692-94183-6
en_US
dc.identifier.uri
http://hdl.handle.net/20.500.11850/228830
dc.description.abstract
This paper reports a microfluidic device that allows for trapping, treatment, and analysis of up to 192 individual giant unilamellar vesicles (GUVs) to study the translocation of fluorescently labeled cell-penetrating peptides (CPPs) across model membranes by fluorescence correlation spectroscopy (FCS). The results indicate that the composition of the membrane influences the membrane permeability of the tested CPPs.
en_US
dc.language.iso
en
en_US
dc.publisher
Chemical and Biological Microsystems Society
en_US
dc.subject
Fluorescence correlation spectroscopy (FCS)
en_US
dc.subject
Giant unilamellar vesicles (GUVs)
en_US
dc.subject
Permeation
en_US
dc.subject
Membrane translocation
en_US
dc.subject
Cell-penetrating peptides (CPPs)
en_US
dc.title
Combination of a microfluidic device and fluorescence correlation spectroscopy to study peptide translocation across model membranes
en_US
dc.type
Other Conference Item
ethz.book.title
21st International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2017)
en_US
ethz.pages.start
967
en_US
ethz.pages.end
968
en_US
ethz.event
21st International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS 2017)
en_US
ethz.event.location
Savannah, GA, USA
en_US
ethz.event.date
October 22-26, 2017
en_US
ethz.notes
Extended abstract. Poster presentation on October 23, 2017.
en_US
ethz.grant
Engineering of hybrid cells using lab-on-chip technology
en_US
ethz.publication.place
San Diego, CA
en_US
ethz.publication.status
published
en_US
ethz.leitzahl
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02060 - Dep. Biosysteme / Dep. of Biosystems Science and Eng.
en_US
ethz.leitzahl
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02060 - Dep. Biosysteme / Dep. of Biosystems Science and Eng.::03807 - Dittrich, Petra / Dittrich, Petra
en_US
ethz.leitzahl.certified
ETH Zürich::00002 - ETH Zürich::00012 - Lehre und Forschung::00007 - Departemente::02060 - Dep. Biosysteme / Dep. of Biosystems Science and Eng.::03807 - Dittrich, Petra / Dittrich, Petra
ethz.grant.agreementno
681587
ethz.grant.agreementno
681587
ethz.grant.fundername
EC
ethz.grant.fundername
EC
ethz.grant.funderDoi
10.13039/501100000780
ethz.grant.funderDoi
10.13039/501100000780
ethz.grant.program
H2020
ethz.grant.program
H2020
ethz.date.deposited
2018-01-15T14:38:38Z
ethz.source
FORM
ethz.eth
yes
en_US
ethz.availability
Metadata only
en_US
ethz.rosetta.installDate
2018-03-09T16:40:18Z
ethz.rosetta.lastUpdated
2022-03-29T05:49:39Z
ethz.rosetta.versionExported
true
ethz.COinS
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