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Open access
Date
2017Type
- Conference Paper
ETH Bibliography
yes
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Abstract
The ability to precisely control the three-dimensional orientation of micrometer-sized biological samples is critical for its phenotypic investigation. We develop an acoustic wave-based microfluidic device that can be used for the trapping and rotational manipulation of single plant cells. Resonant acoustic excitation of air-filled microbubbles generates localized vortices that can be used for the controlled three-dimensional rotation of single cells. We compare the rotational capabilities of microbubble-generated vortices with that of vortices generated by vibration of solid microstructures. We demonstrate the rotational capabilities of the device using single plant cells, the pollen grain. Show more
Permanent link
https://doi.org/10.3929/ethz-b-000225733Publication status
publishedExternal links
Book title
3rd CIRP Conference on BioManufacturingJournal / series
Procedia CIRPVolume
Pages / Article No.
Publisher
ElsevierEvent
Subject
Acoustofluidic; Acoustic Rotation; Single Cells; ImagingOrganisational unit
03627 - Nelson, Bradley J. / Nelson, Bradley J.
09700 - Ahmed, Daniel / Ahmed, Daniel
Funding
SNF_166110 - Mechanical Basis for the Convergent Evolution of Sensory Hairs in Animals and Plants (SNF)
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ETH Bibliography
yes
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