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Autor(in)
Datum
2024Typ
- Journal Article
ETH Bibliographie
yes
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Abstract
Due to their efficient production of reactive oxygen species (ROS) under visible light irradiation, fullerenes (C₆₀ and C₇₀) are useful photosensitizers for applications in photodynamic therapy (PDT). To be suitable as medicines, water-soluble fullerene materials were developed by complexation or conjugation with biocompatible polymers such as poly(vinylpyrrolidone) (PVP) and polyethylene glycol (PEG), and their ROS generation abilities were investigated. In addition, a C₆₀-tripod molecule was synthesized for the modification of AFM tips and used for spatially and temporally controlled oxidative damage of DNA origami immobilized on the surface. Mehr anzeigen
Publikationsstatus
publishedExterne Links
Zeitschrift / Serie
Journal of Synthetic Organic Chemistry, JapanBand
Seiten / Artikelnummer
Verlag
Society of Organic Synthetic Chemistry, JapanFörderung
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183660 - Porphyrin-based imaging probe for the detection of oncogene promoter quadruplex DNA (SNF)
ETH-21 15-2 - MRI probe for the in vivo imaging of atherosclerosis (ETHZ)
ETH-45 19-1 - Spatially and temporally controlled manipulation of DNA origami by chemically modified AFM tip (ETHZ)
ETH-36 20-2 - ROS-responsive MRI probe for in vivo imaging (ETHZ)
ETH Bibliographie
yes
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