METABOLIC REGULATION; Metabolomics; METABOLISM (MICROORGANISMS); METABOLISM (BIOCHEMISTRY); METABOLISMUS (MIKROORGANISMEN); METABOLOMIK (BIOCHEMIE); METABOLISM (PHYSIOLOGY); POST-TRANSLATIONAL PROTEIN MODIFICATION; Posttranslational modification; POSTTRANSLATIONELLE PROTEINMODIFIKATION; Posttranslational regulation; STOFFWECHSELWEGE UND STOFFWECHSELZYKLEN (BIOCHEMIE); Mass spectrometry; MASSENSPEKTROMETRIE; PHOSPHORYLATION, DEPHOSPHORYLATION (BIOCHEMISTRY)