Doctoral Thesis
Neueste Zugänge
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Tunable Plasmonic Molecular Junctions in Gold Nanoparticle Superlattices
(2024)Under electromagnetic excitation, the free electrons in metallic nanoparticles can oscillate collectively, supporting localized surface plasmon resonances (LSPRs). This resonance behaviour allows individual nanoparticles to collect light from a region larger than its physical size and confine the electromagnetic field to subwavelength dimensions. The plasmonic capacitive coupling between adjacent nanoparticles can promote such ...Doctoral Thesis -
The OB-fold and beta-lactamase-like domain of ComEC and their role during natural transformation
(2024)Doctoral Thesis -
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Measuring behaviors in songbird groups
(2024)To truly comprehend the brain's complexity, we must closely examine behavior in real-world settings. Neuroscience has traditionally focused on studying behavior in controlled lab environments, but this approach may not fully capture the brain's natural workings. By observing behavior in more natural contexts, we can gain valuable insights into brain function and understand it on a higher, computational level. This top-down approach can ...Doctoral Thesis -
Engineering Colloidal Gels: Microscopic Design, Macroscopic Characterization and Applications
(2024)Doctoral Thesis -
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New Approaches in the Study and Application of Ribosomal Peptide Natural Products
(2024)Natural products are molecules from nature that increase the fitness of living organisms but are not strictly required for survival. Additionally, natural products are frequently used as medicinal drugs due to their intrinsically favorable properties for binding, inhibiting, or activating pharmaceutically relevant targets. Recent technological advances have renewed the interest in the discovery and application of natural products, ...Doctoral Thesis -
3D PRINTING ARCHITECTURE - Open Framework for Binder Jetting in Construction
(2024)The construction sector stands at a critical juncture, facing the dual challenges of increasing productivity and reducing environmental impact. Over the next 30 years, the world’s building stock is anticipated to double in response to the growing urban population, while the industry is also expected to achieve "net-zero carbon" within the same timeframe. The strategies to address these challenges will significantly affect global sustainability ...Doctoral Thesis -
Mechanistically Guided Predictive Modeling of Stoichiometric Elimination Reactions of Palladium (II) Complexes
(2024)The understanding of chemical mechanisms allows for the accurate prediction of the concentration of chemical species in a reaction over time and therefore the outcome of a reaction. Given the success of this approach, in the past decade focus has shifted to trying to predict the outcome of reactions given only the reaction conditions, with some degree of success. It is reasonable to assume that an approach to this problem that places ...Doctoral Thesis -
Charge-Tagged Cyclopentadienone Iron Complexes: Mechanistic Studies Using Mass Spectrometry for Catalytic Hydrogenation Reactions
(2024)Cyclopentadienone iron complexes, also referred to as Knölker catalysts, have emerged as promising catalysts for the reduction of ketones, aldehydes, and imines. They constitute the iron analogues to the ruthenium based Shvo catalysts and offer the possibility to enable the same chemistry as the ruthenium based system with use of a widely available first-row transition metal. While there is a consensus on the operating reaction mechanism, ...Doctoral Thesis -
Unbiased Identification of CD4+ T Cell Epitopes from the Intestinal Microbiota
(2024)The immune system is comprised of a dynamic and tightly regulated network of molecular and cellular interactions, orchestrating in harmony to protect the host from invading pathogens while maintaining tolerance to self-antigens and innocuous commensal bacteria. The symbiotic relationship between the host and intestinal microbiota plays a crucial role in shaping the host's innate and adaptive immune systems. Due to their involvement in ...Doctoral Thesis -
Understanding Macroeconomic Dynamics: Insights from Output Gaps and Firm Surveys
(2024)Doctoral Thesis -
Stochastic Approximation on Riemannian Manifolds and the Space of Measures
(2024)Stochastic approximation methods are a class of iterative algorithms that play an essential role in applications involving noisy and incomplete observations. Rooted in the seminal works of Robbins and Monro (1951) and Kiefer and Wolfowitz (1952), this class of iterative processes drive a system towards a specified objective despite noise and bias. Stochastic approximation methods have become increasingly important in fields like statistics ...Doctoral Thesis -
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Hematopoietic Stem Cell Fate Decision: The Interplay of Signaling Dynamics, Cytokines, and Bone Marrow Niches
(2024)The dynamics of ERK and p38 MAPK signaling pathways are essential for deciphering how hematopoietic stem cells (HSCs) process environmental signals to determine their fate and function. Traditional methods often fail to capture the transient complexities of these signaling events in live cells. To address this, we utilized fluorescent biosensors and time-lapse imaging to track ERK and p38 MAPK signaling in live, individual HSCs derived ...Doctoral Thesis -